Pure reason unbound to spatial-temporal world; concerned with ontological analysis i.e. the reasoning on the nature of being for various entities e.g. philosophy is concerned with the substance of reason, natural theology is concerned with the nature of the divine, computing has to do with the nature and operations on discrete knowledge.
Exploration of some landscape/vista i.e. associated with every body of knowledge is a domain e.g. for biology it is living organisms, economics has social order as its vista, anatomy is concerned with the nature of living forms.
Principles of production i.e. those rules by which production of goods and services may be most effectively carried out.
Appeal through the senses